progeria
Four Scenarios to Link Progeria to Aging
It is educational, but should be read with the caveat that the author has a strong conviction that the TOR gene is central in the aging process: “Here I discuss four potential scenarios, comparing progeria with both normal and accelerated aging. This reveals further indications of rapamycin both for accelerated aging in obese and for progeria. … Scenario 1. Progerin is detectable in normal cells from normal elderly humans. In normal human fibroblasts, telomere damage during replicative senescence activates progerin production. In theory, progerin can accumulate. In this scenario, normal agin
source :http://www.fightaging.org/archives/2011/07/four-scenarios-to-link-progeria-to-aging.php
Progeria Studies Shed Light On Rare Premature Aging Disorder
New research could offer help to kids with a rare condition that causes them to age at 10 times the normal rate.
Signs of progeria — which include hair loss, a disproportionally large head, visib…
source :http://www.huffingtonpost.com/2011/07/01/progeria-studies-research_n_888678.html
Rare Disease of Progeria Offers Clues to Normal Aging – Health …
per suggests that short or damaged telomeres activate the production of progerin.
Francis Collins, head of the NIH and an author of today’s study, says the paper’s findings offer a new insight into aging. Some researchers thought of aging as a “passive running-down,” he tells the Health Blog. Instead, it appears that “it is an active program to take cells near the end of the life span and make sure they don’t teeter on the brink very long but actually head over the cliff.” Progerin, says Collins, is a key factor in “sending them over the cliff.”
Scientists s
source :http://blogs.wsj.com/health/2011/06/13/rare-disease-of-progeria-offers-clues-to-normal-aging/
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